Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17153412 | 0.73 | — | — | |
| SCHEMBL15730059 | 0.68 | FFAR3 (0.33) | CYP2C19TSHRNFKB1FFAR3SLC22A12 | |
| SCHEMBL18793 | 0.67 | CYP2C19 (0.38) | CYP2C19TSHRFFAR3SLC22A12 | |
| SCHEMBL6897915 | 0.65 | FFAR3 (0.35) | CYP2C19FFAR3SLC22A12 | |
| SCHEMBL9756179 | 0.65 | FFAR3 (0.35) | CYP2C19TSHRNFKB1FFAR3SLC22A12 | |
| SCHEMBL17481679 | 0.64 | FFAR3 (0.33) | CYP2C19FFAR3 | |
| SCHEMBL4581131 | 0.64 | FFAR3 (0.38) | CYP2C19TSHRNFKB1FFAR3 | |
| Bicarbonate SCHEMBL3824750 | 0.63 | CA1 (0.36) | CYP2C19TSHRNFKB1FFAR3 | |
| SCHEMBL17153343 | 0.62 | — | — | |
| SCHEMBL8099795 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190694-A1 | PYRIDINE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9637469-B2 | Pyridine derivative | TEIJIN PHARMA LIMITED (JP) | 2017-05-02 | — | — | US | disclosed |
| US-20150284358-A1 | PYRIDINE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-10-08 | — | — | US | disclosed |
| WO-2014077285-A1 | PYRIDINE DERIVATIVE | 帝人ファーマ株式会社 (JP) | 2014-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284358-A1 | PYRIDINE DERIVATIVE | HPRT1, XDH, NUDT1 | CYP2C19 2209/4885TSHR 3577/4885NFKB1 3188/4885 |
| US-20170190694-A1 | PYRIDINE DERIVATIVE | HPRT1, XDH, NUDT1 | CYP2C19 2209/4885TSHR 3577/4885NFKB1 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.