Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527837 | 0.80 | ACE (0.39) | — | |
| SCHEMBL13409194 | 0.76 | ENPEP (0.47) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL23260782 | 0.76 | BMP1 (0.49) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL22316165 | 0.75 | FOLH1 (0.62) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL25602938 | 0.74 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL25602936 | 0.74 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL25602934 | 0.74 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL25602931 | 0.74 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL22315882 | 0.74 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLABMP1ANPEP | |
| SCHEMBL22315435 | 0.74 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLABMP1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014075137-A1 | PEPTIDES INCORPORATING AMINO-SUBSTITUTED LACTAMS FOR TREATMENT OF RETINOPATHY | BIODIEM LIMITED (AU) | 2014-05-22 | — | — | WO | disclosed |