Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730967 | 0.80 | FOLH1 (0.39) | — | |
| SCHEMBL17992737 | 0.77 | PAX8 (0.31) | PAX8 | |
| SCHEMBL24588345 | 0.72 | PAX8 (0.37) | PAX8 | |
| SCHEMBL19934757 | 0.72 | ACE (0.43) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL13436818 | 0.71 | ALDH1A1 (0.38) | MAPTMMP1 | |
| SCHEMBL21135087 | 0.71 | BMP1 (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL19934701 | 0.71 | BMP1 (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21134710 | 0.71 | BMP1 (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21153275 | 0.71 | BMP1 (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL24581091 | 0.71 | PAX8 (0.50) | PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085896-B1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED SOMATOSTATIN ANALOGS | DEVELOGEN ISRAEL LTD (IL) | 2007-05-16 | — | — | EP | disclosed |