Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CBX7 | O95931 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573088 | 0.93 | RARB (0.34) | ALDH1A1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL1573145 | 0.93 | RARB (0.34) | ALDH1A1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL4507759 | 0.92 | KDM4E (0.36) | ALDH1A1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL3947583 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KMT2AKDM4EHPGDTSHR | |
| SCHEMBL1572762 | 0.87 | SRD5A2 (0.39) | ALDH1A1KMT2AKDM4ERAB9ATP53 | |
| SCHEMBL4514569 | 0.84 | MAPT (0.36) | ALDH1A1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL4500669 | 0.84 | LMNA (0.34) | ALDH1A1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL1573306 | 0.83 | POLB (0.36) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL3943244 | 0.81 | BRAF (0.37) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4509609 | 0.80 | LNPEP (0.42) | ALDH1A1KDM4EHPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2018165-A1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | Sanofi-Aventis (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007080325-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2007-07-19 | — | — | WO | disclosed |