SCHEMBL15733748

SCHEMBL15733748

CO[Si](OC(C)C)(OC(C)C)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.44
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
PTPN5 P54829 1/20 0.35
KDM4E B2RXH2 2/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738722 0.97 KIF11 (0.44) KIF11ALOX5APFEN1RAB9ASMN1; SMN2
SCHEMBL15734853 0.95 CYP3A4 (0.35) KIF11ALOX5APFEN1RAB9ASMN1; SMN2
SCHEMBL15737400 0.91 CYP3A4 (0.35) KIF11ALOX5APFEN1RAB9ASMN1; SMN2
SCHEMBL15734596 0.91 KIF11 (0.48) KIF11PTPN5PSEN1PSEN2APH1B
SCHEMBL15735843 0.89 RXRA (0.41) KIF11AKR1C3AKR1C2PSEN1PSEN2
SCHEMBL15737455 0.86 RXRA (0.41) KIF11AKR1C3AKR1C2PSEN1PSEN2
SCHEMBL15734895 0.86 KIF11 (0.39) KIF11IDO1
SCHEMBL15735806 0.86 KIF11 (0.54) KIF11ALOX5APFEN1RAB9ASMN1; SMN2
SCHEMBL15733872 0.85 ALDH1A1 (0.43) KIF11SMN1; SMN2NPSR1AKR1C3AKR1C2
SCHEMBL15735022 0.83 NPC1 (0.34) RAB9ASMN1; SMN2NPSR1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed