Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573150 | 0.94 | CNR1 (0.34) | TP53KMT2AMAPTNPC1GRIN2B | |
| SCHEMBL1573272 | 0.91 | TP53 (0.33) | TP53KMT2AMAPTNPC1GRIN2B | |
| SCHEMBL1573430 | 0.85 | ADRA2A (0.35) | TP53KMT2AMAPTNPC1LMNA | |
| SCHEMBL1573152 | 0.77 | SMN1; SMN2 (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL697680 | 0.77 | SMN1; SMN2 (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL698417 | 0.77 | SMN1; SMN2 (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1573151 | 0.75 | CYP26A1 (0.34) | TP53KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL697679 | 0.75 | CYP26A1 (0.34) | TP53KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL698416 | 0.75 | CYP26A1 (0.34) | TP53KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL697288 | 0.74 | NPC1 (0.34) | TP53KMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |