Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573397 | 0.94 | TP53 (0.32) | TP53KMT2AMAPTNPC1GRIN2B | |
| SCHEMBL1573272 | 0.89 | TP53 (0.33) | TP53KMT2AMAPTNPC1GRIN2B | |
| SCHEMBL1573430 | 0.83 | ADRA2A (0.35) | TP53KMT2AMAPTNPC1LMNA | |
| SCHEMBL1573149 | 0.76 | PTGES (0.40) | PTGESALOX5PPARGPPARAKMT2A | |
| SCHEMBL697680 | 0.75 | SMN1; SMN2 (0.41) | KMT2AMAPT | |
| SCHEMBL1573152 | 0.75 | SMN1; SMN2 (0.41) | KMT2AMAPT | |
| SCHEMBL698417 | 0.75 | SMN1; SMN2 (0.41) | KMT2AMAPT | |
| SCHEMBL697335 | 0.74 | MAPK1 (0.36) | TP53LMNA | |
| SCHEMBL1573151 | 0.73 | CYP26A1 (0.34) | TP53KMT2A | |
| SCHEMBL698416 | 0.73 | CYP26A1 (0.34) | TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |