SCHEMBL1573401

SCHEMBL1573401

N#Cc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)ccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 19/20 0.58
BCAT1 P54687 19/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8188639 0.90 BCAT2 (0.61) BCAT2BCAT1
SCHEMBL24826936 0.84 BCAT1 (0.62) BCAT2BCAT1
SCHEMBL29779349 0.84 BCAT1 (0.62) BCAT2BCAT1
SCHEMBL29779301 0.81 BCAT1 (0.79) BCAT2BCAT1
SCHEMBL23195555 0.81 BCAT1 (0.79) BCAT2BCAT1
SCHEMBL7038819 0.80 BCAT1 (0.72) BCAT2BCAT1
SCHEMBL7033756 0.79 BCAT2 (0.57) BCAT2BCAT1
SCHEMBL9274567 0.78 TDP1 (0.50) BCAT2BCAT1
SCHEMBL9423250 0.77 BCAT1 (0.48) BCAT2BCAT1
SCHEMBL6815503 0.76 BCAT1 (0.54) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585737-B8 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO SPA (IT) 2011-04-13 EP disclosed
US-7754880-B2 Uracils having a herbicidal activity ISAGRO RICERCA S.R.L. (IT) 2010-07-13 US disclosed
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US disclosed
EP-1585737-A2 URACILS HAVING A HERBICIDAL ACTIVITY Isagro Ricerca S.r.l. (IT) 2005-10-19 EP disclosed
WO-2004056785-A2 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025591-A1 New uracils having a herbicidal activity UNG, DDT, UMPS BCAT2 770/4885BCAT1 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.