SCHEMBL15734937

SCHEMBL15734937

CO[Si](OC)(OC)c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.43
CYP11B2 P19099 3/20 0.43
CYP17A1 P05093 2/20 0.43
PDGFRB P09619 2/20 0.43
PDGFRA P16234 2/20 0.43
NOTUM Q6P988 1/20 0.38
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KIF11 P52732 5/20 0.34
TGFBR1 P36897 1/20 0.33
PGR P06401 1/20 0.33
TRPA1 O75762 1/20 0.33
ABCB1 P08183 1/20 0.33
ABCC1 P33527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733734 0.87 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15736626 0.87 PDGFRB (0.38) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15737700 0.87 PDGFRB (0.38) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15734623 0.87 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15738074 0.85 CYP11B2 (0.36) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15737670 0.84 PDGFRB (0.33) PDGFRBPDGFRANOTUM
SCHEMBL15734169 0.83 CYP11B1 (0.42) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15735780 0.83 CYP11B1 (0.42) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15733540 0.81 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15734829 0.81 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed