SCHEMBL15736626

SCHEMBL15736626

CO[Si](OC)(OC(C)C)c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
CYP11B2 P19099 6/20 0.37
CYP11B1 P15538 5/20 0.37
CYP17A1 P05093 2/20 0.37
PGR P06401 1/20 0.34
NOTUM Q6P988 1/20 0.33
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
GRIN2B Q13224 1/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TRPV3 Q8NET8 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737700 0.97 PDGFRB (0.38) PDGFRBPDGFRACYP11B2CYP11B1CYP17A1
SCHEMBL15736916 0.92 CYP11B2 (0.40) PDGFRBPDGFRACYP11B2CYP11B1CYP17A1
SCHEMBL15738079 0.88 ANPEP (0.34) CYP11B2CYP11B1CYP17A1
SCHEMBL15734491 0.87 ALDH1A1 (0.30) L3MBTL1ALDH1A1MAPT
SCHEMBL15734937 0.87 CYP11B1 (0.43) PDGFRBPDGFRACYP11B2CYP11B1CYP17A1
SCHEMBL15739000 0.84 ANPEP (0.34) CYP11B2CYP11B1CYP17A1
SCHEMBL27959513 0.83 ALDH1A1 (0.30) L3MBTL1ALDH1A1MAPT
SCHEMBL15734683 0.83 NPC1 (0.34) PDGFRBPDGFRACYP17A1ALDH1A1CYP3A4
SCHEMBL15735306 0.83 APP (0.33) AKR1C3AKR1C2TRPV3CYP2C19
SCHEMBL15737458 0.83 ABCB1 (0.32) CYP11B1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed