SCHEMBL15733540

SCHEMBL15733540

CO[Si](O)(OC)c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.41
CYP11B2 P19099 3/20 0.41
CYP17A1 P05093 2/20 0.41
PDGFRB P09619 2/20 0.41
PDGFRA P16234 2/20 0.41
KIF11 P52732 3/20 0.36
NOTUM Q6P988 1/20 0.36
KMO O15229 2/20 0.34
ERN1 O75460 2/20 0.34
IDO1 P14902 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735868 0.86 ANPEP (0.36) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15734829 0.86 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15737338 0.85 CES2 (0.34) PDGFRBPDGFRAALDH1A1
SCHEMBL15734937 0.81 CYP11B1 (0.43) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15734295 0.81 CYP11B1 (0.38) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15735386 0.81 CYP11B1 (0.41) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA
SCHEMBL15734547 0.81 NPC1 (0.38) PDGFRBPDGFRAIDO1ALDH1A1
SCHEMBL15733634 0.81 PTGS2 (0.37) CYP2C19
SCHEMBL15734638 0.80 ABCB1 (0.35) CYP11B1CYP17A1PDGFRBPDGFRANOTUM
SCHEMBL15734169 0.80 CYP11B1 (0.42) CYP11B1CYP11B2CYP17A1PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed