SCHEMBL15735306

SCHEMBL15735306

CO[Si](OC)(OC(C)C)c1ccc(-c2cc(F)c(F)cc2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS2 P35354 7/20 0.32
TRPV3 Q8NET8 1/20 0.31
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15734394 0.97 APP (0.33) APPCYP2C19PTGS2TRPV3PTGS1
SCHEMBL15737749 0.92 TRPV3 (0.33) APPCYP2C19PTGS2TRPV3PTGS1
SCHEMBL15733783 0.87 PTGS2 (0.36) PTGS2PTGS1
SCHEMBL15738496 0.85
SCHEMBL15734543 0.85 APP (0.36) APPCYP2C19AKR1C3AKR1C2MAPK14
SCHEMBL15736626 0.83 PDGFRB (0.38) CYP2C19TRPV3AKR1C3AKR1C2
SCHEMBL15734610 0.82
SCHEMBL15734663 0.82 APP (0.36) APPCYP2C19AKR1C3AKR1C2MAPK14
SCHEMBL15735472 0.80 TRPV3 (0.34) APPCYP2C19PTGS2TRPV3PTGS1
SCHEMBL15737700 0.80 PDGFRB (0.38) CYP2C19TRPV3AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed