SCHEMBL1573554

SCHEMBL1573554

CO/C(=C\C(=O)O)C(C)Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 4/20 0.36
DHODH Q02127 12/20 0.35
PPARG P37231 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2838024 1.00 PPOX (0.36) PPOXDHODHPPARG
SCHEMBL2838020 1.00 PPOX (0.36) PPOXDHODHPPARG
SCHEMBL2834952 0.93 PPOX (0.38) PPOXDHODHPPARG
SCHEMBL1573413 0.93 PPARG (0.34) PPOXDHODHPPARG
SCHEMBL2832645 0.93 PPARG (0.34) PPOXDHODHPPARG
SCHEMBL2832649 0.93 PPARG (0.34) PPOXDHODHPPARG
SCHEMBL1573425 0.91 PPOX (0.35) PPOXDHODHPPARG
SCHEMBL1573647 0.90 PPOX (0.35) PPOXDHODHPPARG
SCHEMBL4572159 0.89 PPOX (0.40) PPOXDHODHPPARG
SCHEMBL2149762 0.89 PPOX (0.40) PPOXDHODHPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585737-B8 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO SPA (IT) 2011-04-13 EP disclosed
US-7754880-B2 Uracils having a herbicidal activity ISAGRO RICERCA S.R.L. (IT) 2010-07-13 US disclosed
US-20060025591-A1 New uracils having a herbicidal activity ISEM S.R.L. (IT) 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025591-A1 New uracils having a herbicidal activity UNG, DDT, UMPS PPOX 2168/4885DHODH 47/4885PPARG 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.