Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HAT1 | O14929 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1573635 | 0.91 | MTOR (0.47) | MEN1KMT2ATDP1GABBR2GABBR1 | |
| SCHEMBL1573478 | 0.84 | MTOR (0.54) | MEN1KMT2ATDP1GABBR2GABBR1 | |
| Iodomethane SCHEMBL1573608 | 0.80 | MTOR (0.48) | MEN1KMT2ATDP1LMNACYP3A4 | |
| Perchlorate SCHEMBL1573231 | 0.79 | MTOR (0.47) | MEN1KMT2ATDP1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL1573359 | 0.78 | LMNA (0.46) | MEN1KMT2ASLC6A9CNR1TDP1 | |
| SCHEMBL9853045 | 0.75 | MEN1 (0.56) | MEN1KMT2ASLC6A9SLC6A5CNR1 | |
| Benzoic Acid SCHEMBL27522254 | 0.72 | TSHR (0.53) | MEN1KMT2ASLC6A9SLC6A5GABBR2 | |
| SCHEMBL1780965 | 0.72 | AKT1 (0.47) | CNR1TDP1LMNA | |
| SCHEMBL4227305 | 0.70 | MTOR (0.58) | MEN1KMT2ASLC6A9SLC6A5CNR1 | |
| SCHEMBL1155162 | 0.70 | GABBR2 (0.48) | MEN1KMT2ATDP1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888064-B1 | BENZTROPINAMINE ANALOGS AS DOPAMINE UPTAKE INHIBITORS | US GOV HEALTH & HUMAN SERV (US) | 2011-04-13 | — | — | EP | disclosed |