Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573478 | 0.93 | MTOR (0.54) | MTORRAB9AGRM7TSHRCYP3A4 | |
| Oxalic Acid SCHEMBL1573558 | 0.91 | MEN1 (0.46) | TSHRCYP3A4LMNAKMT2AMEN1 | |
| Iodomethane SCHEMBL1573608 | 0.88 | MTOR (0.48) | MTORRAB9AGRM7TSHRCYP3A4 | |
| Perchlorate SCHEMBL1573231 | 0.86 | MTOR (0.47) | MTORRAB9AGRM7TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL1573359 | 0.82 | LMNA (0.46) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL6280523 | 0.77 | MTNR1A (0.51) | RAB9AKMT2AL3MBTL1MTNR1AMTNR1B | |
| Oxalic Acid SCHEMBL6423864 | 0.74 | LMNA (0.47) | LMNAHSD17B10KMT2AMTNR1AMTNR1B | |
| SCHEMBL10029043 | 0.74 | RAB9A (0.54) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL18943737 | 0.74 | MTNR1A (0.49) | RAB9AKMT2AMTNR1AMTNR1BMEN1 | |
| Malonic Acid SCHEMBL18006516 | 0.74 | GABBR2 (0.52) | LMNAKMT2AMTNR1AMTNR1BGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888064-B1 | BENZTROPINAMINE ANALOGS AS DOPAMINE UPTAKE INHIBITORS | US GOV HEALTH & HUMAN SERV (US) | 2011-04-13 | — | — | EP | disclosed |