SCHEMBL1573580

SCHEMBL1573580

[N]C(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.47
TSHR P16473 2/20 0.47
F2 P00734 1/20 0.47
TRPA1 O75762 1/20 0.43
HTR2A P28223 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
CYP2D6 P10635 1/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.39
HRH1 P35367 1/20 0.39
MTOR P42345 1/20 0.39
RAB9A P51151 1/20 0.39
GRM7 Q14831 1/20 0.39
MAPK1 P28482 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3904186 0.74 SLC6A2 (0.63) DPP4TSHRF2HTR2ATAAR1
SCHEMBL295579 0.74 GABRA1 (0.48) TSHRCYP2D6SRCLMNAMTOR
SCHEMBL2968554 0.73
SCHEMBL4166272 0.73
SCHEMBL4165369 0.73
SCHEMBL4701869 0.73
SCHEMBL11334471 0.73
SCHEMBL27907795 0.69 SLC6A2 (0.67) DPP4TSHRF2HTR2ATAAR1
SCHEMBL144 0.69 SLC6A2 (0.67) DPP4TSHRF2HTR2ATAAR1
SCHEMBL448348 0.69 DPP4 (0.53) DPP4TSHRF2HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069688-B1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC AMINO COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-10-01 EP claimed
EP-4051673-B1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-09-24 EP claimed
EP-3941912-B1 PESTICIDALLY ACTIVE AZOLE AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-13 EP claimed
EP-3935053-B1 PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 EP claimed
JP-54106455-A None JP disclosed
EP-3619213-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2020-03-11 EP disclosed
WO-2018202494-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2018-11-08 WO disclosed
WO-2015193217-A1 BET-PROTEIN INHIBITING DIHYDROPYRIDO[2,3-B]PYRAZINONE DERIVATIVES WITH PARA-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2015-12-23 WO disclosed
US-8530593-B2 Catalyst compounds and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-10 US disclosed
WO-2011056432-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 WO disclosed
US-20110098431-A1 Catalyst Compounds and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2011-04-28 US disclosed
EP-1888064-B1 BENZTROPINAMINE ANALOGS AS DOPAMINE UPTAKE INHIBITORS US GOV HEALTH & HUMAN SERV (US) 2011-04-13 EP disclosed
EP-1888064-A1 BENZTROPINAMINE ANALOGS AS DOPAMINE UPTAKE INHIBITORS Government of the United States of America, Represented by the Secretary, Department of Health and Human Services (US) 2008-02-20 EP disclosed
WO-2006135715-A1 BENZTROPINAMINE ANALOGS AS DOPAMINE UPTAKE INHIBITORS GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-12-21 WO disclosed
EP-0635021-B1 PROCESS FOR PRODUCING DERIVATIVES OF BIS(AMINOMETHYL) PHOSPHINIC ACID HOECHST AG (DE) 1996-10-09 EP disclosed
EP-0635021-A1 PROCESS FOR PRODUCING DERIVATIVES OF BIS(AMINOMETHYL) PHOSPHINIC ACID. HOECHST AG (DE) 1995-01-25 EP disclosed
WO-1993020086-A1 PROCESS FOR PRODUCING DERIVATIVES OF BIS(AMINOMETHYL) PHOSPHINIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-14 WO disclosed
US-4725600-A Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-16 US disclosed
EP-0168262-A2 Pyrimidine derivatives, processes for preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-15 EP disclosed
JP-S54106455-A PREPARATION OF BENZOPHENONAZINES MITSUBISHI GAS CHEM CO INC 1979-08-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098431-A1 Catalyst Compounds and Use Thereof PAM, AAAS, PAOX DPP4 806/4885TSHR 4358/4885F2 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.