SCHEMBL15736331

SCHEMBL15736331

CCC(CC)(O[SiH3])c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 3/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
TRPA1 O75762 1/20 0.33
PTGS2 P35354 2/20 0.32
PTGS1 P23219 1/20 0.32
KIF11 P52732 5/20 0.31
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
NOTUM Q6P988 1/20 0.30
RIPK1 Q13546 1/20 0.30
PGR P06401 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733939 0.87 ANPEP (0.33) CYP17A1KIF11
SCHEMBL15737637 0.86 KCNN4 (0.33) TRPA1RIPK1
SCHEMBL15733843 0.83 CYP17A1 (0.42) CYP17A1PTGS2KIF11AR
SCHEMBL15738456 0.83 PTGS2 (0.34) PTGS2PTGS1
SCHEMBL15735887 0.82 RXRA (0.34) CYP17A1CYP11B1PTGS2PTGS1KIF11
SCHEMBL15733671 0.81 TAAR1 (0.46) CYP17A1CYP11B1CYP11B2PTGS2PTGS1
SCHEMBL15736547 0.80 KIF11 (0.48) KIF11
SCHEMBL15734909 0.79 PTGER3 (0.31)
SCHEMBL15734620 0.78 CYP17A1 (0.36) CYP17A1CYP11B1CYP11B2PDGFRBPDGFRA
SCHEMBL15735778 0.78 CYP17A1 (0.41) CYP17A1CYP11B1CYP11B2PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed