SCHEMBL15736451

SCHEMBL15736451

CCC(CC)(O[SiH3])c1ccc(-c2ccc(F)cc2F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.37
GRM2 Q14416 2/20 0.36
HTR2A P28223 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
DHFR P00374 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.35
TTR P02766 1/20 0.35
ALB P02768 1/20 0.35
HMGB1 P09429 1/20 0.35
HPGD P15428 1/20 0.35
CXCL12 P48061 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
ACMSD Q8TDX5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738456 0.85 PTGS2 (0.34) APPAKR1C3AKR1C2RORCPTGS2
SCHEMBL15733843 0.82 CYP17A1 (0.42) ALDH1A1PTGS2KIF11IDO1AGXT
SCHEMBL15734909 0.82 PTGER3 (0.31)
SCHEMBL15735581 0.81 CYP17A1 (0.35) KDM4EMEN1USP2ALDH1A1LMNA
SCHEMBL15736768 0.80 APP (0.42) APPGRM2HTR2AKDM4EMEN1
SCHEMBL15737907 0.80 APP (0.35) APPGRM2HTR2AKDM4EMEN1
SCHEMBL15738375 0.79
SCHEMBL15735887 0.78 RXRA (0.34) PTGS2PTGS1KIF11
SCHEMBL15733671 0.78 TAAR1 (0.46) PTGS2PTGS1KIF11AGXT
SCHEMBL15736331 0.77 CYP17A1 (0.38) PTGS2PTGS1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed