SCHEMBL15736624

SCHEMBL15736624

CC(C)(O[SiH3])c1ccc(F)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.36
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
CHRM3 P20309 1/20 0.32
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31
CHRNB1 P11230 1/20 0.31
CHRNB2 P17787 1/20 0.31
SLC6A2 P23975 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CHRND Q07001 1/20 0.31
PDE2A O00408 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735778 0.85 CYP17A1 (0.41)
SCHEMBL15737768 0.78 MEN1 (0.35) CES2CES1
SCHEMBL15734848 0.76 APP (0.38) AKR1C3AKR1C2
SCHEMBL15734968 0.76 SMN1; SMN2 (0.37) KCNN4NFE2L2ALDH1A1ALOX15
SCHEMBL15735195 0.75 KCNN4 (0.40) KCNN4HDAC3HDAC1HDAC2HDAC6
SCHEMBL828570 0.75 ALDH1A1 (0.46) KCNN4HDAC3HDAC1HDAC2HDAC6
SCHEMBL3950869 0.75 ESR1 (0.44) KCNN4HDAC3HDAC1HDAC2HDAC6
SCHEMBL15737637 0.75 KCNN4 (0.33) KCNN4CHRM3PDE2AIDO1
SCHEMBL15735429 0.73 KCNN4 (0.43) KCNN4HDAC3HDAC1HDAC2HDAC6
SCHEMBL15737758 0.73 ANPEP (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed