SCHEMBL15736671

SCHEMBL15736671

O[Si](O)(O)Cc1cc(F)cc(F)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CYP17A1 P05093 1/20 0.31
CYP21A2 P08686 1/20 0.31
CYP11B1 P15538 1/20 0.31
DAO P14920 1/20 0.31
DBH P09172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736611 0.77 CES2 (0.37) CA1CES2CES1
SCHEMBL15735660 0.77 TAAR1 (0.50) IDO1CYP11B1
SCHEMBL15734036 0.75 IDO1 (0.38) IDO1CA12CA1CA9CES2
SCHEMBL27959403 0.75 IDO1 (0.39) IDO1CA12CA1CA9MEN1
SCHEMBL15738500 0.75 IDO1 (0.39) IDO1CA12CA1CA9MEN1
SCHEMBL15733439 0.75 MAPK14 (0.35) IDO1CA12CA1CA9MEN1
SCHEMBL15734925 0.74 IDO1 (0.46) IDO1
SCHEMBL15735851 0.72 IDO1 (0.36) IDO1CA12CA1CA9MEN1
SCHEMBL15734667 0.72 RIPK1 (0.33) CA12CA1CA9CES2CES1
SCHEMBL15736105 0.72 IDO1 (0.35) IDO1CA12CA1CA9CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed