Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573863 | 1.00 | MAPK1 (0.53) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL1573866 | 1.00 | MAPK1 (0.53) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL1573767 | 0.90 | MAPK1 (0.48) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL1573769 | 0.90 | MAPK1 (0.48) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL853692 | 0.84 | HTR3E (0.55) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL853693 | 0.84 | HTR3E (0.55) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL3082532 | 0.83 | MEN1 (0.60) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL3082531 | 0.83 | MEN1 (0.60) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL4015597 | 0.83 | HCAR3 (0.41) | MAPK1HCAR3ALDH1A1GAAMEN1 | |
| SCHEMBL3526469 | 0.83 | HCAR3 (0.52) | MAPK1HCAR3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |