Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349270 | 0.80 | ASAH1 (0.56) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL260982 | 0.79 | SLC22A12 (0.54) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| Hydrochloric Acid SCHEMBL30581596 | 0.78 | SLC22A12 (0.53) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL4423022 | 0.77 | SLC22A12 (0.55) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL496975 | 0.75 | ELANE (0.70) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL1087434 | 0.74 | CHEK1 (0.60) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| Indazole Carboxamide SCHEMBL42505 | 0.74 | SLC22A12 (0.53) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL2025416 | 0.74 | SLC22A12 (0.56) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| Fluoromethane SCHEMBL28001608 | 0.74 | ASAH1 (0.53) | ASAH1RAB9ANPC1KMT2ATFPI2 | |
| SCHEMBL28135895 | 0.74 | ASAH1 (0.67) | ASAH1RAB9ANPC1KMT2ATFPI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |
| EP-1713779-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | Sanofi-Aventis Deutschland GmbH (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073199-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-08-11 | — | — | WO | disclosed |