SCHEMBL1573845

SCHEMBL1573845

CC(=O)ON1C(COc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)=NNN1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574595 0.94
SCHEMBL1573521 0.89 DHODH (0.30) DHODH
SCHEMBL1573587 0.83
SCHEMBL6205437 0.80 DHODH (0.31) DHODH
SCHEMBL6226436 0.80 DHODH (0.30) DHODH
SCHEMBL6230385 0.79 PPOX (0.39) DHODH
SCHEMBL10576855 0.79 BCAT1 (0.34) DHODH
SCHEMBL10573646 0.78 PPOX (0.36) DHODH
SCHEMBL10577815 0.78 PPOX (0.32) DHODH
SCHEMBL10579666 0.78 BCAT1 (0.36) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585737-B8 URACILS HAVING A HERBICIDAL ACTIVITY ISAGRO SPA (IT) 2011-04-13 EP disclosed