Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574568 | 0.83 | RBP4 (0.40) | MAP2K4MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1573835 | 0.83 | GAA (0.45) | MAP2K4MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1573854 | 0.81 | RBP4 (0.45) | MAP2K4MAPK1MAPK6RBP4 | |
| SCHEMBL1574198 | 0.81 | TP53 (0.47) | MAP2K4LIPEMAPK1MAPK6CYP2C19 | |
| SCHEMBL1573919 | 0.81 | HRH4 (0.47) | MAP2K4ALDH1A1MAPK1MAPK6 | |
| SCHEMBL1573862 | 0.80 | ALDH1A1 (0.44) | MAP2K4POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1573971 | 0.80 | MAP2K4 (0.42) | MAP2K4ALDH1A1MAPK1MAPK6CYP2C19 | |
| SCHEMBL1573920 | 0.78 | MAP2K4 (0.41) | MAP2K4MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1573781 | 0.78 | MAP2K4 (0.41) | MAP2K4ALDH1A1MAPK1MAPK6RBP4 | |
| SCHEMBL1573680 | 0.78 | RBP4 (0.43) | MAP2K4KMT2AMAPK1MAPK6RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |