Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972121 | 0.80 | MAPK1 (0.37) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL23820014 | 0.78 | MAPK1 (0.36) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL11995145 | 0.77 | CA2 (0.41) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL3970320 | 0.74 | MAPK1 (0.36) | MAPK1MEN1KMT2ACYP2C9SLC22A12 | |
| SCHEMBL12960882 | 0.73 | HTT (0.41) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL12928755 | 0.73 | CA12 (0.34) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL10094606 | 0.73 | CA12 (0.34) | CA12CA1CA2CA9MAPK1 | |
| SCHEMBL25427690 | 0.72 | SLC22A12 (0.40) | MAPK1MEN1KMT2ACYP2C9SLC22A12 | |
| SCHEMBL255968 | 0.69 | GPR3 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL25428408 | 0.68 | CASP3 (0.43) | MAPK1MEN1KMT2ACYP2C9SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014078813-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2014-05-22 | — | — | WO | disclosed |