Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195335 | 0.79 | — | — | |
| SCHEMBL7338033 | 0.78 | — | — | |
| SCHEMBL2131358 | 0.78 | — | — | |
| SCHEMBL8569309 | 0.78 | — | — | |
| Potassium Ion SCHEMBL11273635 | 0.76 | — | — | |
| SCHEMBL4958791 | 0.76 | — | — | |
| SCHEMBL9737991 | 0.73 | MGLL (0.33) | — | |
| SCHEMBL11778389 | 0.73 | — | — | |
| SCHEMBL10757043 | 0.72 | — | — | |
| SCHEMBL9564037 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106727540-A | A kind of application of the 1,3,4 thiadiazoles disulfide compounds containing phenylurea based structures | 天津理工大学 | 2017-05-31 | — | — | CN | claimed |
| US-9296973-B2 | Lubricating oil composition for use in all transmission systems | PETROCHINA COMPANY LIMITED (CN) | 2016-03-29 | — | — | US | claimed |
| US-20140162919-A1 | LUBRICATING OIL COMPOSITION FOR USE IN ALL TRANSMISSION SYSTEMS | PETROCHINA COMPANY LIMITED (CN) | 2014-06-12 | — | — | US | claimed |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PROLX PHARMACEUTICALS CORPORATION (CA) | 2003-09-18 | — | — | US | claimed |
| JP-9071753-A | — | — | None | — | — | JP | disclosed |
| JP-11131036-A | — | — | None | — | — | JP | disclosed |
| US-10640630-B2 | Elastomeric composites containing modified fillers and functionalized elastomers | CABOT CORPORATION (US) | 2020-05-05 | — | — | US | disclosed |
| EP-2819854-B1 | ELASTOMERIC COMPOSITES CONTAINING MODIFIED FILLERS AND FUNCTIONALIZED ELASTOMERS | CABOT CORP (US) | 2020-04-15 | — | — | EP | disclosed |
| CN-106701282-B | Gear oil composition and preparation method thereof | 上海禾泰特种润滑科技股份有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-106727540-A | A kind of application of the 1,3,4 thiadiazoles disulfide compounds containing phenylurea based structures | 天津理工大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106727539-A | A kind of application of the 1,3,4 thiadiazoles disulfide compounds containing aniline based structures | 天津理工大学 | 2017-05-31 | — | — | CN | disclosed |
| US-9296973-B2 | Lubricating oil composition for use in all transmission systems | PETROCHINA COMPANY LIMITED (CN) | 2016-03-29 | — | — | US | disclosed |
| WO-2006023658-A2 | METHOD OF PRE-SELECTING PATIENTS FOR ANTI-VEGF, ANTI-HIF-1 OR ANTI-THIOREDOXIN THERAPY | PROLX PHARMACEUTICALS CORP. (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2005007108-A2 | ASYMMETRIC DISULFIDES AND METHODS OF USING SAME | PROLX PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| US-20040116496-A1 | Asymmetric Disulfides and methods of using same | PROLX PHARMACEUTICALS CORP. | 2004-06-17 | — | — | US | disclosed |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PROLX PHARMACEUTICALS CORPORATION (CA) | 2003-09-18 | — | — | US | disclosed |
| US-6552060-B1 | Inhibits abnormal cellular proliferation and restores or prevents inhibition of cellular apoptosis | PROLX PHARMACEUTICALS, INC. | 2003-04-22 | — | — | US | disclosed |
| JP-H11131036-A | ADHESIVE COMPOSITION | TOKUYAMA CORP | 1999-05-18 | — | — | JP | disclosed |
| US-5853435-A | Polymeric amine-heterocyclic reaction products as fuel and lubricant antiwear, detergency and cleanliness additives | MOBIL OIL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| JP-H0971753-A | METAL SURFACE TREATMENT | TOKUYAMA CORP | 1997-03-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PRDX3, PDIA5, PRDX5 | KMT2A 4152/4885MEN1 3374/4885NPC1 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.