Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157403 | 0.76 | KMT2A (0.33) | — | |
| SCHEMBL2131358 | 0.72 | — | — | |
| SCHEMBL8569309 | 0.72 | — | — | |
| SCHEMBL7338033 | 0.72 | — | — | |
| SCHEMBL4958791 | 0.70 | — | — | |
| SCHEMBL10757043 | 0.67 | — | — | |
| SCHEMBL9564037 | 0.67 | — | — | |
| SCHEMBL4636124 | 0.65 | — | — | |
| SCHEMBL9563950 | 0.65 | ALDH1A1 (0.44) | — | |
| SCHEMBL9785769 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042937-A1 | Antifreeze concentrate containing inhibitors to prevent localized corrosion of aluminum and solder alloy | BASF WYANDOTTE CORPORATION (US) | 1982-01-06 | — | — | EP | disclosed |