Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CA1 | P00915 | 3/20 | 0.77 |
| ▸ | CA2 | P00918 | 3/20 | 0.77 |
| ▸ | UQCRB | P14927 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | RORA | P35398 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657557 | 1.00 | KMT2A (1.00) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL812679 | 0.91 | ALDH1A1 (0.83) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL540915 | 0.86 | CA1 (0.85) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL11793140 | 0.86 | CA1 (0.85) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL13433558 | 0.85 | ALDH1A1 (0.73) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL1040954 | 0.85 | ALDH1A1 (0.73) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL7178237 | 0.83 | UQCRB (1.00) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL95623 | 0.83 | ALDH1A1 (0.71) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL27811906 | 0.83 | ALDH1A1 (0.71) | KMT2AALDH1A1MEN1MAPTCYP1A2 | |
| SCHEMBL4573249 | 0.83 | KMT2A (0.71) | KMT2AALDH1A1MEN1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |