SCHEMBL13433558

SCHEMBL13433558

Cc1ccc(S(=O)(=O)Nc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.73
MAPT P10636 5/20 0.73
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
CA1 P00915 2/20 0.73
CA2 P00918 2/20 0.73
CYP1A2 P05177 1/20 0.73
CYP3A4 P08684 1/20 0.73
CYP2C19 P33261 1/20 0.73
UQCRB P14927 1/20 0.73
HDAC3 O15379 2/20 0.66
HDAC11 Q96DB2 2/20 0.66
HDAC8 Q9BY41 2/20 0.66
HDAC6 Q9UBN7 2/20 0.66
RORA P35398 1/20 0.66
CA12 O43570 1/20 0.64
CA9 Q16790 1/20 0.64
LMNA P02545 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
GAA P10253 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1040954 1.00 ALDH1A1 (0.73) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL812679 0.93 ALDH1A1 (0.83) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL2005010 0.87 CA12 (0.81) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL15740331 0.85 KMT2A (1.00) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL27811906 0.85 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL20657557 0.85 KMT2A (1.00) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL7178237 0.85 UQCRB (1.00) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL95623 0.85 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL13615341 0.84 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL12042475 0.84 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055356-A1 CELLULOSE ACYLATE LAMINATE FILM, METHOD FOR PRODUCING SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20100055356-A1 CELLULOSE ACYLATE LAMINATE FILM, METHOD FOR PRODUCING SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed