Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750112 | 0.83 | ENPP2 (0.38) | MAPK1NPSR1AKR1B1SERPINE1AKR1B10 | |
| SCHEMBL15708010 | 0.83 | ENPP2 (0.38) | MAPK1NPSR1AKR1B1SERPINE1AKR1B10 | |
| SCHEMBL15740404 | 0.82 | TMEM97 (0.36) | MAPK1NPSR1AKR1B1 | |
| SCHEMBL15740440 | 0.82 | KCNH2 (0.36) | MAPK1NPSR1AR | |
| SCHEMBL2125266 | 0.78 | SERPINE1 (0.49) | SERPINE1 | |
| SCHEMBL15740469 | 0.77 | CYP2C19 (0.34) | MAPK1NPSR1 | |
| SCHEMBL19767197 | 0.76 | MAPK1 (0.37) | MAPK1NPSR1SERPINE1 | |
| SCHEMBL19767208 | 0.76 | PRKAA2 (0.38) | MAPK1NPSR1SERPINE1 | |
| SCHEMBL19767180 | 0.76 | MAPK1 (0.37) | MAPK1NPSR1SERPINE1 | |
| SCHEMBL15740437 | 0.75 | MAPK1 (0.38) | MAPK1NPSR1SERPINE1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |