Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740404 | 0.88 | TMEM97 (0.36) | CYP2C19TMEM97MAPK1NPSR1 | |
| SCHEMBL15740408 | 0.85 | PTGES (0.38) | CYP2C19KCNH2TMEM97MAPK1NPSR1 | |
| SCHEMBL15740426 | 0.85 | HRH3 (0.42) | TMEM97MAPK1NPSR1SIRT6 | |
| SCHEMBL15740392 | 0.84 | PCSK9 (0.35) | PCSK9 | |
| SCHEMBL15740364 | 0.84 | SIRT6 (0.41) | CYP2C19KCNH2TMEM97MAPK1NPSR1 | |
| SCHEMBL2126360 | 0.83 | SERPINE1 (0.45) | — | |
| SCHEMBL15708028 | 0.83 | ENPP2 (0.40) | PCSK9 | |
| SCHEMBL15727618 | 0.83 | ENPP2 (0.40) | PCSK9 | |
| SCHEMBL15740405 | 0.82 | AR (0.34) | CYP2C19KCNH2TMEM97MAPK1SIRT6 | |
| SCHEMBL15740437 | 0.82 | MAPK1 (0.38) | CYP2C19KCNH2TMEM97MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |