Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 4/20 | 0.40 |
| ▸ | GIPR | P48546 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740864 | 1.00 | MAPT (0.41) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15741032 | 0.92 | GCGR (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15741030 | 0.92 | GCGR (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15740804 | 0.89 | NPC1 (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15740816 | 0.89 | NPC1 (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15740801 | 0.89 | NPC1 (0.43) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL13109486 | 0.87 | ITGB3 (0.49) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15741031 | 0.86 | KMT2A (0.41) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15741061 | 0.84 | KMT2A (0.40) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL15741115 | 0.84 | RAB9A (0.41) | MAPTALDH1A1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922821-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2019-07-31 | — | — | EP | claimed |
| US-20150299123-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC. | 2015-10-22 | — | — | US | claimed |
| EP-2922821-A1 | S1P AND/OR ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2015-09-30 | — | — | EP | claimed |
| WO-2014081756-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-05-30 | — | — | WO | claimed |
| EP-2922821-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2019-07-31 | — | — | EP | disclosed |
| US-9771326-B2 | S1P and/or ATX modulating agents | BIOGEN MA INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20150299123-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC. | 2015-10-22 | — | — | US | disclosed |
| EP-2922821-A1 | S1P AND/OR ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081756-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299123-A1 | S1P AND/OR ATX MODULATING AGENTS | ENPP2, S1PR1, S1PR2 | MAPT 3910/4885ALDH1A1 4063/4885NPC1 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.