SCHEMBL22863234

SCHEMBL22863234

CC(C)=CCC/C(C)=C/CCC1(C)Oc2c(c(O)cc3c2CN(CCCCC(=O)O)C3=O)CC1O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 8/20 0.36
▸ FNTA P49354 2/20 0.35
▸ FNTB P49356 2/20 0.35
▸ NR1H4 Q96RI1 2/20 0.34
▸ BACE1 P56817 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ APP P05067 2/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ PSEN1 P49768 1/20 0.33
▸ NR1I2 O75469 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23941206 1.00 ALOX5 (0.36) ALOX5FNTAFNTBNR1H4BACE1
SCHEMBL22863201 0.99 ALOX5 (0.35) ALOX5FNTAFNTBNR1H4BACE1
SCHEMBL23941210 0.99 ALOX5 (0.35) ALOX5FNTAFNTBNR1H4BACE1
SCHEMBL13746651 0.95 APP (0.35) ALOX5NR1H4BACE1APPPTPN1
SCHEMBL22863208 0.95 ALOX5 (0.42) ALOX5BACE1NR1I2
SCHEMBL22863355 0.94 ALOX5 (0.37) ALOX5NR1H4BACE1APPPTPN1
SCHEMBL23941477 0.94 ALOX5 (0.37) ALOX5NR1H4BACE1APPPTPN1
SCHEMBL22863225 0.93 KDM4E (0.33) ALOX5KDM4EALDH1A1HPGD
SCHEMBL9880206 0.90 ALOX5 (0.44) ALOX5NR1H4BACE1APPPTPN1
SCHEMBL9880205 0.90 ALOX5 (0.44) ALOX5NR1H4BACE1APPPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
EP-4337193-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION Biogen MA Inc. (US) 2024-03-20 — — EP disclosed
EP-4326258-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 Biogen MA Inc. (US) 2024-02-28 — — EP disclosed
CN-117295497-A Pharmaceutical composition for treating cerebral infarction 渤健马萨诸塞州股份有限公司 2023-12-26 — — CN disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 — — US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 — — US disclosed
WO-2022240810-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION BIOGEN MA INC. (US) 2022-11-17 — — WO disclosed
WO-2022226013-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 BIOGEN MA INC. (US) 2022-10-27 — — WO disclosed
US-20220218664-A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG SHOWA UNIVERSITY (JP) 2022-07-14 — — US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
US-20210000794-A1 Drug and Method of Treating or Preventing Renal Disease Using Drug SHOWA UNIVERSITY (JP) 2021-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 ALOX5 1492/4885FNTA 3811/4885FNTB 3931/4885
US-20220218664-A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG SLC5A2, SLC5A1, IAPP ALOX5 71/4885FNTA 599/4885FNTB 1486/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 ALOX5 302/4885FNTA 1134/4885FNTB 1126/4885
US-20210000794-A1 Drug and Method of Treating or Preventing Renal Disease Using Drug REN, ATP6V1B1, SLC10A1 ALOX5 117/4885FNTA 2070/4885FNTB 3838/4885
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION PSD, SCN7A, MBOAT7 ALOX5 3129/4885FNTA 572/4885FNTB 835/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 ALOX5 1492/4885FNTA 3811/4885FNTB 3931/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 ALOX5 302/4885FNTA 1134/4885FNTB 1126/4885
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 SMPD1, SMPD3, MBOAT7 ALOX5 2914/4885FNTA 1004/4885FNTB 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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