Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027652 | 0.86 | LMNA (0.58) | KDM4EALDH1A1LMNAHDAC1HDAC3 | |
| SCHEMBL15745146 | 0.85 | HDAC1 (0.50) | KDM4EALDH1A1LMNAHDAC1HDAC3 | |
| SCHEMBL6318770 | 0.84 | HDAC1 (0.58) | ALDH1A1HDAC1KMT2AMEN1HPGD | |
| SCHEMBL14635730 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL24203553 | 0.76 | HDAC1 (0.49) | HDAC1HDAC6KMT2AMEN1POLB | |
| SCHEMBL28545988 | 0.76 | CYP1B1 (0.66) | ALDH1A1LMNAHDAC1HDAC3HDAC2 | |
| SCHEMBL18537445 | 0.75 | HDAC1 (0.60) | KDM4EALDH1A1LMNAHDAC1HDAC3 | |
| SCHEMBL23563379 | 0.74 | KMT2A (0.64) | KDM4ELMNAHDAC1HDAC3HDAC2 | |
| SCHEMBL6347785 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL30153490 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926121-B1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | OPTI MEDICAL SYSTEMS INC (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9360474-B2 | Multi-layer device for selectively determining magnesium ion | OPTI MEDICAL SYSTEMS, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-9360474-B2 | Multi-layer device for selectively determining magnesium ion | OPTI MEDICAL SYSTEMS, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | IDEXX LABORATORIES, INC. (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | IDEXX LABORATORIES, INC. (US) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | ORAI1, CACYBP, CASR | KDM4E 2862/4885ALDH1A1 4806/4885LMNA 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.