Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744698 | 0.86 | KDM4E (0.57) | LMNAKDM4EALDH1A1HDAC3HDAC1 | |
| SCHEMBL916911 | 0.83 | KMT2A (0.65) | LMNAKDM4EALDH1A1HDAC1MEN1 | |
| SCHEMBL14015910 | 0.81 | MEN1 (0.47) | LMNAKDM4EALDH1A1HDAC3HDAC1 | |
| SCHEMBL10819259 | 0.80 | PIN1 (0.68) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14635730 | 0.77 | KDM4E (0.63) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28545988 | 0.76 | CYP1B1 (0.66) | LMNAALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL10819260 | 0.76 | ALDH1A1 (0.60) | LMNAKDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL18537445 | 0.76 | HDAC1 (0.60) | LMNAKDM4EALDH1A1HDAC3HDAC1 | |
| SCHEMBL30153490 | 0.75 | ALDH1A1 (1.00) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6347785 | 0.75 | ALDH1A1 (1.00) | LMNAKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097725-B2 | Luminescent indicator dye and optical sensor | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| EP-1817290-B1 | LUMINESCENT INDICATOR DYE AND OPTICAL SENSOR | ROCHE DIAGNOSTICS GMBH (DE) | 2008-11-12 | — | — | EP | disclosed |