Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | LPL | P06858 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045433 | 0.92 | CA2 (0.45) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL14355511 | 0.87 | CA2 (0.50) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL19214431 | 0.87 | CA2 (0.50) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL15744763 | 0.83 | ACHE (0.42) | CA2CA1NPC1RAB9AMEN1 | |
| SCHEMBL27251936 | 0.81 | CA2 (0.50) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL8974204 | 0.81 | CA2 (0.54) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL13018298 | 0.78 | CA2 (0.41) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL2602434 | 0.77 | ACHE (0.48) | CA2CA1MEN1KMT2AACHE | |
| SCHEMBL1853563 | 0.77 | CA2 (0.84) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL19214435 | 0.76 | CA2 (0.61) | CA2LPLLIPGCA1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |