Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602434 | 0.93 | ACHE (0.48) | ACHELMNAWDR5KMT2ACYP3A4 | |
| SCHEMBL15744775 | 0.83 | CA2 (0.50) | ACHEWDR5KMT2ANPC1RAB9A | |
| SCHEMBL29002128 | 0.81 | ABL1 (0.38) | LMNAKMT2ACYP3A4ESR2TDP1 | |
| SCHEMBL15744764 | 0.81 | APP (0.42) | ACHELMNAWDR5ALDH1A1CA1 | |
| SCHEMBL15744765 | 0.81 | APP (0.42) | ACHELMNAWDR5ALDH1A1CA1 | |
| SCHEMBL13556727 | 0.81 | PPARG (0.46) | ACHEPPARGPPARAPOLBMAPT | |
| SCHEMBL14477632 | 0.80 | MEN1 (0.33) | KMT2AESR2MEN1CA1CA2 | |
| SCHEMBL13556726 | 0.79 | PPARG (0.45) | ACHEKMT2APPARGPPARAMEN1 | |
| SCHEMBL13556728 | 0.79 | PPARG (0.45) | ACHEKMT2APPARGPPARAMEN1 | |
| SCHEMBL25661896 | 0.79 | MMP3 (0.44) | LMNAKMT2ANPSR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |