Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28010903 | 0.92 | CYP1A2 (0.47) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL31634147 | 0.91 | SIRT5 (0.47) | TDP1L3MBTL1ALDH1A1HIF1AMEN1 | |
| SCHEMBL378787 | 0.90 | ALDH1A1 (0.51) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL34462112 | 0.87 | TDP1 (0.44) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL31482564 | 0.87 | TDP1 (0.44) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL15744796 | 0.85 | KMT2A (0.59) | TDP1L3MBTL1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL15882797 | 0.85 | PDGFRB (0.55) | TDP1L3MBTL1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL378788 | 0.84 | CYP1A2 (0.52) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL23199799 | 0.83 | PDGFRB (0.55) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL31458565 | 0.82 | TDP1 (0.51) | TDP1L3MBTL1ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104434927-A | Application of bicyclopentanoperhydrophenanthrene malonate B in preparing hypotensive drugs | UNIV JILIN AGRICULTURAL | 2015-03-25 | — | — | CN | disclosed |