SCHEMBL15745643

SCHEMBL15745643

Cc1ccc(C(=O)c2ccc(C)c(C(=O)O)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.62
ALDH1A1 P00352 4/20 0.59
LMNA P02545 1/20 0.59
AKR1C3 P42330 2/20 0.58
POLB P06746 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 2/20 0.50
AKR1C2 P52895 1/20 0.46
CDC25A P30304 1/20 0.46
CDC25B P30305 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 1/20 0.44
CSNK2A1 P68400 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15746905 0.92 ALDH1A1 (0.59) SRD5A2ALDH1A1LMNAAKR1C3POLB
SCHEMBL7772602 0.87 POLB (0.70) SRD5A2ALDH1A1LMNAAKR1C3POLB
SCHEMBL69633 0.82 TSHR (0.53) ALDH1A1POLBTDP1L3MBTL1SMN1; SMN2
SCHEMBL7772106 0.81 CDC25A (0.59) SRD5A2ALDH1A1AKR1C3POLBTDP1
SCHEMBL12554042 0.80 SMN1; SMN2 (0.74) SRD5A2ALDH1A1LMNAPOLBTDP1
SCHEMBL11664352 0.80 TSHR (0.52) ALDH1A1POLBTDP1L3MBTL1SMN1; SMN2
Hydrochloric Acid SCHEMBL10448118 0.80 TSHR (0.52) ALDH1A1POLBTDP1L3MBTL1SMN1; SMN2
Hydrochloric Acid SCHEMBL16610510 0.80 TSHR (0.52) ALDH1A1POLBTDP1L3MBTL1SMN1; SMN2
SCHEMBL2622768 0.80 SMN1; SMN2 (0.74) SRD5A2ALDH1A1LMNAPOLBTDP1
SCHEMBL28858438 0.80 TSHR (0.52) ALDH1A1POLBTDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 US disclosed
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed