Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CDC25A | P30304 | 1/20 | 0.61 |
| ▸ | CDC25B | P30305 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203260 | 0.90 | TDP1 (0.84) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL7045921 | 0.90 | TDP1 (0.84) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL30754379 | 0.90 | TDP1 (0.84) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL29440676 | 0.90 | TDP1 (0.84) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL29404709 | 0.88 | POLB (0.80) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL48886 | 0.88 | POLB (0.80) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL6654551 | 0.87 | KDM4E (0.73) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL15745643 | 0.87 | SRD5A2 (0.62) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| SCHEMBL1538420 | 0.86 | POLB (0.67) | POLBTDP1L3MBTL1AKR1C3SRD5A2 | |
| 4-Methylbenzoic Acid SCHEMBL27320298 | 0.86 | ALDH1A1 (0.68) | POLBTDP1L3MBTL1AKR1C3SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870752-B1 | Bulk dyeing using quinophthalone dyestuffs | BAYER AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| EP-0932603-A1 | METHOD FOR PRODUCING 1,8-DIAMINONAPHTHALINES AND THEIR 2,3-DIHYDROPERIMIDINE DERIVATIVES | BAYER AG (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0870752-A1 | Bulk dyeing using quinophthalone dyestuffs | BAYER AG (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1998015533-A1 | METHOD FOR PRODUCING 1,8-DIAMINONAPHTHALINES AND THEIR 2,3-DIHYDROPERIMIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |