Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745656 | 0.88 | POLB (0.39) | POLBARSMN1; SMN2HSD11B1ALDH1A1 | |
| SCHEMBL15746912 | 0.84 | SMN1; SMN2 (0.46) | POLBARSMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL15745647 | 0.82 | ALDH1A1 (0.46) | POLBARSMN1; SMN2HSD11B1ALDH1A1 | |
| SCHEMBL9154318 | 0.79 | POLB (0.52) | POLBSMN1; SMN2ALDH1A1ESR1ESR2 | |
| SCHEMBL15745652 | 0.78 | AR (0.34) | POLBARSMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL15745650 | 0.78 | AR (0.34) | POLBARSMN1; SMN2ALDH1A1 | |
| SCHEMBL15745648 | 0.78 | SMN1; SMN2 (0.34) | POLBARSMN1; SMN2HSD11B1ALDH1A1 | |
| SCHEMBL1816541 | 0.77 | POLB (0.52) | POLBARSMN1; SMN2HSD11B1ALDH1A1 | |
| SCHEMBL15831659 | 0.77 | ESR1 (0.39) | ARHSD11B1ESR1ESR2TSHR | |
| SCHEMBL15745649 | 0.77 | ABCC9 (0.37) | POLBARSMN1; SMN2HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9793483-B2 | Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20140148571-A1 | Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-29 | — | — | US | disclosed |