SCHEMBL15745652

SCHEMBL15745652

Cc1cc(Cc2cc(C)c(N)c(C(C)(O)C(F)(F)F)c2)cc(C(C)(O)C(F)(F)F)c1N

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.34
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SHBG P04278 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
HMGB1 P09429 1/20 0.31
CXCL12 P48061 1/20 0.31
DHFR P00374 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745662 0.85 AR (0.32) ARSMN1; SMN2DHFR
SCHEMBL15733061 0.85 SMN1; SMN2 (0.45) ARPOLBSMN1; SMN2SHBGESR1
SCHEMBL15831660 0.83 AR (0.39) ARSHBGESR1ESR2HMGB1
SCHEMBL15745661 0.82 ADRB2 (0.40) AR
SCHEMBL15745658 0.82 ADRB2 (0.39) AR
SCHEMBL15745659 0.82 AR (0.30) AR
SCHEMBL15745647 0.81 ALDH1A1 (0.46) ARPOLBSMN1; SMN2ALDH1A1
SCHEMBL15745646 0.81 HSPA5 (0.38) ARPOLBDHFR
SCHEMBL15745656 0.79 POLB (0.39) ARPOLBSMN1; SMN2ESR1ALDH1A1
SCHEMBL16838071 0.79 AR (0.36) ARSHBGESR1ESR2HMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-9061253-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-23 US disclosed
US-20140174293-A1 Gas Separation Membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2014-06-26 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed