Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745688 | 0.89 | ESR1 (0.38) | ESR1ESR2ALDH1A1MEN1POLB | |
| SCHEMBL15745962 | 0.86 | NR1H3 (0.36) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL15745685 | 0.86 | ALDH1A1 (0.37) | ESR1ESR2NPSR1ALDH1A1MEN1 | |
| SCHEMBL15745687 | 0.86 | NR1H3 (0.36) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL15745686 | 0.85 | ALDH1A1 (0.44) | ESR1ESR2ALDH1A1POLBKDM4E | |
| SCHEMBL15745814 | 0.76 | APEX1 (0.36) | APEX1ESR1ESR2NPSR1ALDH1A1 | |
| SCHEMBL15746934 | 0.74 | APEX1 (0.37) | APEX1ESR1ESR2NPSR1ALDH1A1 | |
| SCHEMBL15745683 | 0.74 | ALDH1A1 (0.35) | APEX1NPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL85774 | 0.72 | APEX1 (0.61) | APEX1ESR1ESR2NPSR1ALDH1A1 | |
| SCHEMBL15831667 | 0.71 | NR1H3 (0.36) | ESR1ESR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9793483-B2 | Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20140148571-A1 | Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-29 | — | — | US | disclosed |