Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745687 | 0.92 | NR1H3 (0.36) | NR1H3NR1H2ESR1ESR2CA9 | |
| SCHEMBL15745688 | 0.89 | ESR1 (0.38) | NR1H3NR1H2ESR1ESR2ALDH1A1 | |
| SCHEMBL15745690 | 0.86 | APEX1 (0.40) | ESR1ESR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL15745685 | 0.86 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1KDM4EAPP | |
| SCHEMBL15745686 | 0.85 | ALDH1A1 (0.44) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL15831667 | 0.85 | NR1H3 (0.36) | NR1H3NR1H2ESR1ESR2CA9 | |
| SCHEMBL15744802 | 0.84 | NR1H3 (0.36) | NR1H3NR1H2ESR1ESR2CA9 | |
| SCHEMBL12724505 | 0.77 | NR1H2 (0.46) | NR1H3NR1H2ESR1ESR2CA9 | |
| SCHEMBL13929403 | 0.76 | ESR1 (0.47) | NR1H3NR1H2ESR1ESR2CA9 | |
| SCHEMBL2622758 | 0.76 | ESR1 (0.41) | NR1H3NR1H2ESR1ESR2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9050566-B2 | Gas separation membrane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140144324-A1 | Gas Separation Membrane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-29 | — | — | US | disclosed |