SCHEMBL85774

SCHEMBL85774

Cc1ccccc1N1C(=O)c2ccc(C(=O)c3ccc4c(c3)C(=O)N(C)C4=O)cc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.61
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
POLB P06746 1/20 0.60
ALDH1A1 P00352 4/20 0.51
RECQL P46063 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ENPP2 Q13822 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17946428 0.94 APEX1 (0.68) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL14494978 0.90 APEX1 (0.55) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL12225210 0.88 APEX1 (0.57) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL5010574 0.85 ALDH1A1 (0.70) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL10053398 0.82 ALDH1A1 (0.60) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL17327599 0.82 NPSR1 (0.50) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL14154235 0.82 APEX1 (0.53) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL10098939 0.82 ALDH1A1 (0.59) APEX1MEN1KMT2APOLBALDH1A1
SCHEMBL16656166 0.79 KMT2A (0.66) MEN1KMT2APOLBALDH1A1HSD17B10
SCHEMBL25454879 0.79 ESR1 (0.46) APEX1MEN1KMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786870-B2 CMS membrane, method for the production thereof and use thereof Forschungszentrum Jülich GmbH (DE) 2023-10-17 US disclosed
US-11786861-B2 High selectivity polyimide/PES blend hollow fiber membrane for gas separations UOP LLC (US) 2023-10-17 US disclosed
US-20230167588-A1 METHOD OF PREPARING CARBON COMPOSITE FIBER AND CARBON COMPOSITE FIBER KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-06-01 US disclosed
US-9999861-B2 Carbon molecular sieve membranes for nitrogen/methane separation GEORGIA TECH RESEARCH CORPORATION (US) 2018-06-19 US disclosed
US-20180043656-A1 Oriented Multilayer Porous Film LiSo Plastics, L.L.C. (US) 2018-02-15 US disclosed
US-20170157556-A1 METHOD AND SYSTEM FOR PURIFICATION OF NATURAL GAS USING MEMBRANES Air Liquide Advanced Technologies, U.S. LLC (US) 2017-06-08 US disclosed
US-9570752-B2 Negative electrode material for lithium-based batteries GM Global Technology Operations LLC (US) 2017-02-14 US disclosed
US-9446347-B2 Method of obtaining carbon dioxide from a carbon dioxide-containing gas mixture L'Air Liquide Société Anonyme Pour L'Étude Et L'Exploitation Des Procedes Georges Claude (FR) 2016-09-20 US disclosed
US-20150333318-A1 NEGATIVE ELECTRODE MATERIAL FOR LITHIUM-BASED BATTERIES GM Global Technology Operations LLC (US) 2015-11-19 US disclosed
US-20150325831-A1 POLYIMIDE WEB SEPARATOR FOR USE IN AN ELECTROCHEMICAL CELL DUPONT SAFETY & CONSTRUCTION, INC. 2015-11-12 US disclosed
US-8663364-B2 Method of obtaining carbon dioxide from carbon dioxide-containing gas mixture L'Air Liquide, Société Anonyme pour l'Étude et l'Éxploitation des Procédés Georges Claude (FR) 2014-03-04 US disclosed
US-20130133166-A1 Method for Reducing Self Discharge in an Electrochemical Cell E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-05-30 US disclosed
US-20130125358-A1 METHOD FOR REDUCING SELF DISCHARGE IN AN ELECTROCHEMICAL CELL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-05-23 US disclosed
US-8129437-B2 Process for the extraction of hydrogen from a gas mixture SHELL OIL COMPANY (US) 2012-03-06 US disclosed
US-20110247360-A1 Method of Obtaining Carbon Dioxide From Carbon Dioxide-Containing Gas Mixture L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2011-10-13 US disclosed
US-20110239700-A1 Method of Obtaining Carbon Dioxide From Carbon Dioxide-Containing Gas Mixture L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2011-10-06 US disclosed
US-20110138852-A1 Method of Obtaining Carbon Dioxide From Carbon Dioxide-Containing Gas Mixture L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2011-06-16 US disclosed
US-20100317751-A1 PROCESS FOR THE EXTRACTION OF HYDROGEN FROM A GAS MIXTURE SHELL USA, INC. 2010-12-16 US disclosed
US-7404844-B2 Method for making carbon membranes for fluid separation NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-07-29 US disclosed
US-7306754-B2 Membrane and the use thereof UNIVERSITAT TWENTE (NL) 2007-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317751-A1 PROCESS FOR THE EXTRACTION OF HYDROGEN FROM A GAS MIXTURE WIZ, WDR12, SUZ12 APEX1 2894/4885MEN1 2425/4885KMT2A 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.