SCHEMBL15745843

SCHEMBL15745843

OB(O)c1ccccc1CNCCCNCc1ccccc1B(O)O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 5/20 0.58
▸ CA2 P00918 5/20 0.58
▸ CA9 Q16790 4/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ TSHR P16473 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ CHRM2 P08172 8/20 0.50
▸ LIPG Q9Y5X9 1/20 0.50
▸ MPO P05164 1/20 0.49
▸ SLC6A4 P31645 1/20 0.49
▸ GRIN1 Q05586 3/20 0.46
▸ GRIN2A Q12879 3/20 0.46
▸ BCHE P06276 2/20 0.46
▸ ACHE P22303 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745844 0.96 CA12 (0.58) CA12CA2CA9KDM4ETSHR
SCHEMBL6348034 0.93 LIPG (0.56) CA12CA2CA9KDM4ETSHR
SCHEMBL237159 0.89 LIPG (0.47) CA12CA2CA9KDM4ETSHR
SCHEMBL26009770 0.89 LIPG (0.50) CA12CA2CA9KDM4ETSHR
SCHEMBL1700582 0.88 CHRM2 (0.56) CA12CA2CA9KDM4ETSHR
SCHEMBL30253962 0.88 CHRM2 (0.56) CA12CA2CA9KDM4ETSHR
SCHEMBL6352960 0.87 MPO (0.65) LIPGMPOSLC6A4BCHE
SCHEMBL10457529 0.85 SCN8A (0.48) CA12CA2CA9KDM4ETSHR
SCHEMBL13287109 0.84 LIPG (0.48) CA12CA2CA9KDM4ETSHR
SCHEMBL10457527 0.83 CA12 (0.45) CA12CA2CA9TSHRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9970940-B2 Barrier layer for glucose sensor LIGHTSHIP MEDICAL LIMITED (GB) 2018-05-15 — — US disclosed
US-9797909-B2 Sensor LIGHTSHIP MEDICAL LIMITED (GB) 2017-10-24 — — US disclosed
US-20170010274-A1 SENSOR VANTIVE HEALTH GMBH (CH) 2017-01-12 — — US disclosed
US-9476886-B2 Sensor LIGHTSHIP MEDICAL LIMITED (GB) 2016-10-25 — — US disclosed
US-20160178638-A1 Glucose Sensor Molecule VANTIVE HEALTH GMBH (CH) 2016-06-23 — — US disclosed
US-9222941-B2 Glucose sensor molecules LIGHTSHIP MEDICAL LIMITED (GB) 2015-12-29 — — US disclosed
US-20150219663-A1 SENSOR LIGHTSHIP MEDICAL LIMITED (GB) 2015-08-06 — — US disclosed
US-8940542-B2 Sensor Lighthouse Medical Limited (GB) 2015-01-27 — — US disclosed
US-20140349307-A1 Barrier Layer for Glucose Sensor ARES CAPITAL CORPORATION 2014-11-27 — — US disclosed
US-20140234982-A1 SENSOR LIGHTSHIP MEDICAL LIMITED (GB) 2014-08-21 — — US disclosed
US-20140147934-A1 Glucose sensor molecules ARES CAPITAL CORPORATION 2014-05-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160178638-A1 Glucose Sensor Molecule GPR119, GCKR, IRS1 CA12 2225/4885CA2 1316/4885CA9 1931/4885
US-20140147934-A1 Glucose sensor molecules GPR119, GCKR, IRS1 CA12 2296/4885CA2 1269/4885CA9 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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