SCHEMBL1574598

SCHEMBL1574598

O=C(Cc1c[nH]c2ccccc12)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.68
LTA4H P09960 1/20 0.63
ECE1 P42892 1/20 0.61
ACE P12821 4/20 0.60
P2RY14 Q15391 1/20 0.60
ALOX15 P16050 1/20 0.60
ITGB2 P05107 1/20 0.58
ICAM1 P05362 1/20 0.58
ITGAL P20701 1/20 0.58
MME P08473 1/20 0.58
MEN1 O00255 1/20 0.58
POLB P06746 1/20 0.58
HTT P42858 1/20 0.58
SLC6A2 P23975 1/20 0.58
FNTA P49354 1/20 0.58
FNTB P49356 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30069244 1.00 KMT2A (0.68) KMT2ALTA4HECE1ACEP2RY14
SCHEMBL503091 1.00 KMT2A (0.68) KMT2ALTA4HECE1ACEP2RY14
SCHEMBL29557188 1.00 KMT2A (0.68) KMT2ALTA4HECE1ACEP2RY14
SCHEMBL3728145 0.92 ALOX15 (0.70) KMT2AACEP2RY14ALOX15ITGB2
SCHEMBL13278205 0.92 ALOX15 (0.70) KMT2AACEP2RY14ALOX15ITGB2
SCHEMBL29987387 0.92 ALOX15 (0.70) KMT2AACEP2RY14ALOX15ITGB2
SCHEMBL11591677 0.90 ECE1 (0.71) KMT2ALTA4HECE1ACEP2RY14
SCHEMBL28046779 0.90 ECE1 (0.71) KMT2ALTA4HECE1ACEP2RY14
SCHEMBL2489043 0.88 KMT2A (0.72) KMT2ALTA4HACEALOX15ITGB2
SCHEMBL6138173 0.87 P2RY14 (0.56) KMT2AECE1ACEP2RY14ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1378574-B1 Enhanced production of taxol and taxanes by cell cultures of taxus species PHYTON HOLDINGS LLC (US) 2011-04-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
US-20250340495-A1 SLUDGE-DERIVED PLANT BIOSTIMULANT, AND DIRECTIONAL PREPARATION METHOD AND APPLICATION THEREOF UNIV TONGJI (CN) 2025-11-06 US disclosed
US-20250197898-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-06-19 US disclosed
US-12227780-B2 Isothiocyanate containing Brassicaceae products and method of preparation thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-02-18 US disclosed
US-20220160802-A1 METHODS AND COMPOSITIONS FOR PROMOTING HEALTH IN A SUBJECT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2022-05-26 US disclosed
US-20200255872-A1 Isothiocyanate containing Brassicaceae Products and Method of Preparation Thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-08-13 US disclosed
EP-3688179-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE Commonwealth Scientific and Industrial Research Organisation (AU) 2020-08-05 EP disclosed
WO-2019060963-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2019-04-04 WO disclosed
US-9465040-B2 Method for profiling phytohormone levels in plant tissue BASF PLANT SCIENCE COMPANY GMBH (DE) 2016-10-11 US disclosed
US-20140147925-A1 Method for Profiling Phytohormone Levels in Plant Tissue BASF PLANT SCIENCE COMPANY GMBH (DE) 2014-05-29 US disclosed
EP-2697640-A1 METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE BASF Plant Science Company GmbH (DE) 2014-02-19 EP disclosed
WO-2012140603-A1 METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE BASF PLANT SCIENCE COMPANY GMBH (DE) 2012-10-18 WO disclosed