Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ACE | P12821 | 4/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.56 |
| ▸ | ITGAL | P20701 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869259 | 0.93 | KMT2A (0.69) | KMT2AACELTA4HALDH1A1MAPT | |
| SCHEMBL28587519 | 0.91 | ALOX15 (0.64) | KMT2AACELTA4HMEN1HCRTR1 | |
| SCHEMBL2959306 | 0.91 | ALOX15 (0.64) | KMT2AACELTA4HMEN1HCRTR1 | |
| SCHEMBL2956712 | 0.91 | ALOX15 (0.64) | KMT2AACELTA4HMEN1HCRTR1 | |
| SCHEMBL1574598 | 0.88 | KMT2A (0.68) | KMT2AACELTA4HMEN1ALOX15 | |
| SCHEMBL503091 | 0.88 | KMT2A (0.68) | KMT2AACELTA4HMEN1ALOX15 | |
| SCHEMBL30069244 | 0.88 | KMT2A (0.68) | KMT2AACELTA4HMEN1ALOX15 | |
| SCHEMBL29557188 | 0.88 | KMT2A (0.68) | KMT2AACELTA4HMEN1ALOX15 | |
| SCHEMBL28359802 | 0.87 | ALDH1A1 (0.61) | KMT2AACEALDH1A1MAPTGAA | |
| SCHEMBL28359800 | 0.87 | ALDH1A1 (0.61) | KMT2AACEALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379053-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR CANCER | Takeda Pharmaceutical Company Limited (JP) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010076896-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR CANCER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-07-08 | — | — | WO | disclosed |