SCHEMBL15746151

SCHEMBL15746151

CCc1ccc(Oc2ccc(C)c(C)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.46
SLC6A4 P31645 4/20 0.46
KCNH2 Q12809 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
KMT2A Q03164 2/20 0.45
LMNA P02545 1/20 0.45
GFER P55789 1/20 0.45
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 1/20 0.44
HAO1 Q9UJM8 1/20 0.42
TDP1 Q9NUW8 3/20 0.42
NPC1 O15118 1/20 0.40
ESR1 P03372 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
MAPK1 P28482 1/20 0.39
ESR2 Q92731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10268647 0.86 TEAD4 (0.45) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL15186278 0.85 LTA4H (0.45) SMN1; SMN2L3MBTL1KMT2ALMNAMAPT
SCHEMBL15186252 0.85 LTA4H (0.50) SMN1; SMN2LMNAHPGDNPC1RAB9A
SCHEMBL20143446 0.83 HTR2A (0.34) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL15186258 0.83 HTR2A (0.47) HTR2ASLC6A4KCNH2
SCHEMBL47874 0.82 KMT2A (0.57) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL28384106 0.81 HTR2A (0.39) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL19449193 0.81 HTR2A (0.44) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL24576256 0.80 KMT2A (0.43) HTR2ASLC6A4KCNH2SMN1; SMN2L3MBTL1
SCHEMBL10825619 0.80 HPGD (0.48) SMN1; SMN2L3MBTL1KMT2ALMNAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9056285-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-16 US disclosed
US-20140144325-A1 Gas Separation Membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed