SCHEMBL47874

SCHEMBL47874

Cc1ccc(Oc2ccc(C)c(C)c2)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
LMNA P02545 1/20 0.57
GFER P55789 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.55
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
HAO1 Q9UJM8 1/20 0.53
HTR2A P28223 5/20 0.48
SLC6A4 P31645 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
KCNH2 Q12809 4/20 0.44
ALDH1A1 P00352 4/20 0.43
NR4A1 P22736 1/20 0.42
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47864 0.97 KMT2A (0.60) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL10993100 0.97 KMT2A (0.60) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL13649894 0.90 KMT2A (0.50) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL257610 0.90 KMT2A (0.55) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL10984775 0.90 KMT2A (0.55) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL10259158 0.90 SMN1; SMN2 (0.62) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL9455443 0.90 KMT2A (0.52) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL10990207 0.90 KMT2A (0.55) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL30587868 0.90 KMT2A (0.52) KMT2AL3MBTL1LMNAGFERSMN1; SMN2
SCHEMBL4454151 0.88 LTA4H (0.55) KMT2AL3MBTL1LMNAGFERSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113912620-B Preparation method of 9, 9-bis (trifluoromethyl) -2,3,6, 7-xanthene tetracarboxylic dianhydride 常州市阳光药业有限公司 2022-09-13 CN claimed
CN-113912620-A Preparation method of 9, 9-bis (trifluoromethyl) -2,3,6, 7-xanthene tetracarboxylic dianhydride 常州市阳光药业有限公司 2022-01-11 CN claimed
CN-111303183-A Synthetic method of tetracarboxylic dianhydride with fluorinated rigid structure 浙江中科玖源新材料有限公司 2020-06-19 CN claimed
US-4937389-A HEATING, MIXING WITH METHANOL, COOLING, CRYSTALLIZATION AMOCO CORPORATION (US) 1990-06-26 US claimed
US-4900865-A Method for producing a di-(mono- or poly-)carboxyaryl ether AMOCO CORPORATION (US) 1990-02-13 US claimed
EP-0349218-A2 Separation of 3,3,',4,4'- and 2,3,3',4'-tetramethyldiphenyl ether AMOCO CORPORATION (US) 1990-01-03 EP claimed
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US claimed
JP-2085228-A None JP disclosed
JP-2085228-A None JP disclosed
US-20240239988-A1 SEMICONDUCTOR ELEMENT ENCAPSULATION RESIN COMPOSITION AND SEMICONDUCTOR DEVICE HAVING CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20240239988-A1 SEMICONDUCTOR ELEMENT ENCAPSULATION RESIN COMPOSITION AND SEMICONDUCTOR DEVICE HAVING CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
WO-2024136365-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION AND ELECTRONIC DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-27 WO disclosed
US-4577034-A Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones THE DOW CHEMICAL COMPANY (US) 1986-03-18 US disclosed
US-4562271-A Preparation of 3-alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1985-12-31 US disclosed
EP-0154720-A1 Polyamic acid copolymer solutions for improved semiconductor manufacturing International Business Machines Corporation (US) 1985-09-18 EP disclosed
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US disclosed
US-4485247-A 3-Alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1984-11-27 US disclosed
EP-0125342-A1 Process for preparation of aromatic polycarboxylic acids and intermediates therefor THE UPJOHN COMPANY (US) 1984-11-21 EP disclosed
EP-0008735-A1 Process for the preparation of diphenyl ether carboxylic acids BAYER AG (DE) 1980-03-19 EP disclosed